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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5R1
All Species:
25.15
Human Site:
Y74
Identified Species:
50.3
UniProt:
Q15078
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15078
NP_003876.1
307
34060
Y74
K
V
Q
P
N
S
S
Y
Q
N
N
I
T
H
L
Chimpanzee
Pan troglodytes
XP_001158783
424
45536
Y191
K
V
Q
P
N
S
S
Y
Q
N
N
I
T
H
L
Rhesus Macaque
Macaca mulatta
XP_001113074
307
34072
Y74
K
V
Q
P
N
S
S
Y
Q
N
N
I
T
H
L
Dog
Lupus familis
XP_548274
307
34112
Y74
K
V
Q
P
N
S
S
Y
Q
N
N
I
T
H
L
Cat
Felis silvestris
Mouse
Mus musculus
O35926
369
38896
D110
N
L
L
R
K
G
R
D
G
P
D
G
G
G
T
Rat
Rattus norvegicus
P61810
307
34013
Y74
K
A
Q
P
N
S
S
Y
Q
S
N
I
A
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510972
134
15408
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079141
293
32627
R67
S
T
K
K
K
T
S
R
K
S
T
A
N
N
N
Zebra Danio
Brachydanio rerio
NP_001002515
310
34763
Y74
K
V
Q
P
N
T
T
Y
Q
N
N
V
S
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523535
472
53508
D240
Q
N
Q
N
Q
V
Q
D
I
R
E
E
V
M
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22695
356
39856
S82
L
P
K
S
G
S
S
S
E
A
T
S
S
K
S
Sea Urchin
Strong. purpuratus
XP_794538
375
41683
S89
S
T
G
V
S
T
T
S
L
D
T
N
F
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.2
99.6
99
N.A.
48.5
98.3
N.A.
36.4
N.A.
66.1
79.6
N.A.
35.5
N.A.
35.1
42.1
Protein Similarity:
100
70
99.6
99.6
N.A.
57.9
99
N.A.
40.7
N.A.
79.8
88
N.A.
46.4
N.A.
50.5
57.3
P-Site Identity:
100
100
100
100
N.A.
0
80
N.A.
0
N.A.
6.6
73.3
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
13.3
86.6
N.A.
0
N.A.
40
100
N.A.
13.3
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
9
0
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
17
0
9
9
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
9
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
9
0
9
9
0
0
9
0
0
9
9
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
42
0
0
0
% I
% Lys:
50
0
17
9
17
0
0
0
9
0
0
0
0
9
0
% K
% Leu:
9
9
9
0
0
0
0
0
9
0
0
0
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
9
0
9
50
0
0
0
0
42
50
9
9
17
9
% N
% Pro:
0
9
0
50
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
9
0
59
0
9
0
9
0
50
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
9
9
0
9
0
0
0
0
0
% R
% Ser:
17
0
0
9
9
50
59
17
0
17
0
9
17
0
17
% S
% Thr:
0
17
0
0
0
25
17
0
0
0
25
0
34
0
17
% T
% Val:
0
42
0
9
0
9
0
0
0
0
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _